INCI Name: Sodium hyaluronate

Appearance: Liquid

Purity: 99.9%

MOQ 10kg

Package: 200grams/bottle, 1kg/bag, 5kg/bag

Storage：Store in a cool 2-8 degree, dry place and keep tightly sealed.

Modified sodium hyaluronate is a derivative obtained by modifying the molecular structure of sodium hyaluronate (HA-Na) through chemical, 

physical, or biological approaches. Its core advantages include resistance to enzymatic degradation, prolonged retention, excellent biocompatibility, 

and customizable functionality, significantly expanding the application scope of traditional HA.

The following provides a systematic explanation from three perspectives: mainstream types, core efficacy, and application fields.

I. Main Modification Types and Core Efficacies

1. Acetylated sodium hyaluronate (AcHA)

Enhanced biocompatibility: Hydrophilic backbone + lipophilic acetyl group improve transdermal absorption, allowing deep penetration into the dermis. 

Long-lasting hydration: Double the water absorption capacity, providing hydration for over 12 hours and improving dryness and roughness. 

Healing barrier: Promotes epidermal cell proliferation, enhances stratum corneum toughness, and reduces water loss. 

Film-forming skin-softening: Creates a breathable protective film with a fresh, non-sticky texture that enhances skin elasticity. 

2. Cross-linked sodium hyaluronate (cross-linked HA)

Degradation-resistant + Long-lasting: A dense reticular structure resistant to hyaluronidase degradation, with an in vivo retention time extended 

from 24 hours to several weeks. 

High viscoelasticity: Gel-like consistency with strong support and water retention capabilities, offering remarkable filling, shaping, lubrication, 

and cushioning effects. Antioxidant and soothing: Eliminates free radicals, reduces sun-induced damage and inflammation, and promotes wound healing. 

3. Cationic sodium hyaluronate (e.g., hydroxypropyl trimethyl ammonium chloride HA)

High adsorption capacity: Positive charges静电ally bond with the negative charges of skin/hair, ensuring resistance to rinsing and prolonged adhesion. 

Hair Care and Repair: Restores hair cuticles, reduces static electricity, smooths and strengthens hair, while enhancing its moisture retention and shine. 

4. Low-molecular-weight/enzymatically hydrolyzed sodium hyaluronate

High permeability: With a low molecular weight, it rapidly penetrates into the dermis, enhancing microcirculation and collagen synthesis. 

Promotes repair: Accelerates skin healing, alleviates sensitivity and redness, and is suitable for sensitive skin and postoperative recovery. 

II. Summary of Core Efficacies

Moisturizing and water retention: Hydrophilic groups bind with abundant moisture, providing long-lasting hydration and alleviating dryness. 

Healing Barrier: Promotes epidermal regeneration, enhances skin resilience, and reduces sensitivity. 

Anti-aging and firming: Stimulates collagen synthesis, enhances elasticity, and reduces fine lines. 

Soothing and Anti-inflammatory: Eliminates free radicals, inhibits inflammatory factors, and alleviates redness, swelling, and postoperative discomfort. 

Lubrication Buffer: High viscoelasticity for joint lubrication, ocular hydration, and filling/reshaping effects. 

Permeation enhancer: Improves the transdermal penetration rate of active ingredients, enhances efficacy, and reduces irritation. 

III. Application Fields

1. Cosmetics and skincare products (the most mainstream)

Moisturizing and Repair: Serum, cream, mask, spray – deliver deep hydration and repair the skin barrier. 

Anti-aging and Firming: Anti-aging serum, eye cream, and neck cream to reduce fine lines and enhance elasticity. 

Sun protection and soothing: Sunscreen lotion, post-sun exposure repair, film-forming protection, and reduction of sunburn redness. 

Hair care: Shampoo, conditioner, and hair mask – smooth and strengthen hair while reducing static electricity. 

2. Biopharmaceuticals

Ophthalmology: Eye drops (e.g., RAWCEL), artificial tears, postoperative protective agents, corneal lubricants, dry eye relief agents, and tissue 

repair promoters. Orthopedics: Joint cavity injection of gel to lubricate joints, protect cartilage, and alleviate osteoarthritis pain. 

Aesthetic medical filling: Cross-linked HA gel for injection, used for facial filling, wrinkle reduction, and contouring (e.g., hyaluronic acid). 

Wound healing: Wound dressings and postoperative anti-adhesion gels promote healing and reduce scarring. 

Drug carrier: A targeted delivery system that enhances drug stability and efficacy while reducing side effects. 

3. Medical Devices

Medical dressing: A moist healing dressing that provides hydration, anti-infection properties, and accelerates tissue repair. 

Non-adhesive material: Postoperative isolation gel to reduce intrauterine and intra-abdominal adhesions. 

Tissue engineering: Scaffolding materials that support cell growth and induce tissue regeneration. 

4. Other fields

Health supplement: Oral administration of HA derivatives improves joint health and skin hydration. 

Contact lenses: Lens materials/care solutions to enhance comfort, provide hydration, and prevent dryness. 

IV. Association with Eye Drops (Compatible with the RAWCEL brand)

Modified sodium hyaluronate (particularly acetylated/low molecular weight HA) serves as the core ingredient in premium eye drops:

Simulated tears: Composed of ingredients closely resembling natural tears, providing moisturizing and lubricating effects to alleviate 

dry eye symptoms. 

Corneal repair: Promotes corneal epithelial regeneration, improves ocular surface damage, and reduces inflammation. 

Prolonged retention: Resistant to enzymatic degradation, extending the duration of ocular surface contact and reducing the frequency of application. 

Gentle and Safe: Excellent biocompatibility, non-irritating, and suitable for sensitive eyes