Appearance: white fine powder
Purity: 98% up
Package:100g per bag or bottle
Quality validity: 2 years
MOQ 100G
Efficacy of EGF (Epidermal Growth Factor) and its addition ratio;
EGF (Epidermal Growth Factor) is a discovery awarded the 1986 Nobel Prize in Physiology or Medicine and is widely used in the fields of cosmetics and skincare products.Below is a detailed description of its key effects and addition ratios:
The primary efficacy of EGF
Promote cell regeneration and repair
EGF binds to receptors on the surface of skin cells, activating cell division and proliferation, thereby accelerating skin self-renewal.Particularly suitable for postoperative recovery (e.g., after laser therapy, microneedling, or chemical peeling), significantly reducing recovery time.
Promote collagen production:
EGF stimulates fibroblasts to enhance the synthesis of collagen and elastin, improving skin elasticity, thickness, and firmness, thereby effectively combating aging.
Whitening and spot removal
By altering the ratio of new to old cells and reducing melanin content, skin tone is brightened and pigmented spots gradually fade.
Repair the skin barrier
For skin that has undergone excessive exfoliation, suffered from sun damage, or is chronically dry and damaged, EGF helps rebuild the skin barrier and reduce redness and inflammation.
Remove scars and improve pore texture
It accelerates metabolism, regulates collagen secretion, and exhibits reparative effects on acne scars and post-inflammatory hyperpigmentation. Additionally, it promotes subcutaneous collagen synthesis, leading to pore contraction.
Addition ratio of EGF
There is no linear relationship between EGF concentration and efficacy; higher concentrations do not necessarily yield better results.The following are reference concentrations for different application scenarios:
| Application Scenario | Recommended Concentration | Description |
|---|---|---|
| Daily Maintenance Skincare | 0.001%～0.05% | Low concentrations can produce measurable biological effects |
| Clinically Effective Products | 5～20 ng/mL | Concentration range proven effective by clinical tests |
| Patented Formula (Culture Medium Type) | 0.4～0.8 ng/mL | Used in combination with BSA and cell culture medium |
| High-Concentration Intensive Repair | Not exceeding 100 μg/mL | Caution needed beyond this value, may trigger receptor downregulation |
Usage Instructions:
Higher concentrations are not always preferable: efficacy declines beyond 0.05%, and excessively high concentrations may trigger "receptor downregulation," where cells reduce their EGF receptor count to prevent excessive stimulation, thereby diminishing long-term efficacy.
Stability is critical: EGF is sensitive to light, oxygen, and high temperatures. It is recommended to select products with airless pump heads and opaque packaging, stored at temperatures not exceeding 4°C.
Avoid combining with strong acids or retinoids: High concentrations of fruit acids or retinoid components may compromise the stability of EGF; it is recommended to apply them at intervals of 20–30 minutes.
Recommended synergistic ingredients: hyaluronic acid, ceramide, copper peptides (GHK-Cu), nicotinamide, and other components can enhance the efficacy of EGF.
