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  • Product Name:Acetyl tetrapeptide-2
  • Efficacy:Boosts elastin and collagen, improving skin stiffness
  • Application:Cosmetic ingredients
  • Molecular:C26H39N5O9
Product Details

Amino acid sequence: Ac-Lys-Asp-Val-Tyr (Ac-KDVY)

Molecular formula: C₂₆H₃₉N₅O₉

Molecular weight: 565.62 g/mol

Appearance: White to off-white lyophilized powder

Solubility: Soluble in water; for poor solubility, 1%-10% ammonia solution or bicarbonate buffer solution may be used to enhance solubility.

Purity ≥99%

Storage conditions: Lyophilized powder – store at-80°C for 2 years or at-20°C for 1 year; after dissolution, aliquot and store at-20°C, avoiding repeated freeze-thaw cycles.

Package:100g per bag or bottle

Quality validity: 2 years

MOQ 100G


Core Efficacy

Promote the synthesis of collagen and elastin

Acetyl tetrapeptide-2 upregulates gene expression associated with collagen synthesis and adhesion plaque protein (FAK), significantly enhances type I collagen production, and stimulates the formation of fibronectin, thereby improving skin firmness and reconstructing epidermal structure.

Enhance the activity of FBLN-5 and LOXL-1

It promotes the synthesis and activity of Fibulin-5 (the elastic fiber anchoring protein) and Lysyl oxidase-like protein-1 (LOXL-1), both of which are essential for the proper formation of elastic fibers, thereby effectively combating skin laxity and sagging.

Enhance skin elasticity and firmness

Through multidimensional synergistic effects—promoting the synthesis of type I and III collagen, enhancing the skin's elastic fiber network, improving facial contour, and reducing wrinkles and fine lines.

Strengthen the skin barrier

Supports the skin's natural barrier function, helps retain moisture, enhances skin softness and texture, and improves radiance.

Highly safe, mild, and non-irritating

The acne-inducing rating is 0 (lowest). Its water-soluble formula does not clog pores and is suitable for all skin types, including sensitive skin.


Reference proportions for addition to cosmetics

Drug dosage form

Recommended Addition Amount

explain

Serum/Ampoule

50200 ppm0.005%0.02%

High-concentration essence products, efficacy-oriented

Face Cream/Lotion

10100 ppm0.001%0.01%

Daily Care Products

Eye Cream/Cervical Cream

20100 ppm0.002%0.01%

For the need to enhance firmness in the periorbital and cervical areas

Mask (patch/wash-on type)

50200 ppm0.005%0.02%

Intensive care with short-term high-concentration exposure

Applicable Product Types

Anti-aging/Anti-wrinkle essence and cream

Tightening and enhancement products (for face, neck, and body)

Eye Care Products

Postpartum/Post-exposure Body Care Repair

Post-repair products for medical art treatments

Stria Care Products

Formulation Precautions

Administration timing: Add during the final stage of cosmetic production (low-temperature phase), with temperature not exceeding 40°C, to avoid peptide chain degradation caused by high temperatures.

pH range: The recommended formulation pH should be controlled between 5.0 and 7.0.

Contraindications: Avoid concurrent use with strong acids (high-concentration fruit acids/salicylic acid), strong oxidizing agents, or heavy metal ions.

Synergistic ingredient recommendation: Can be combined with hyaluronic acid, collagen peptides, hexapeptide (acetylated hexapeptide-3), nicotinamide, etc., to achieve synergistic effects.

Dissolution method: First, completely dissolve the lyophilized powder with a small amount of pure water or buffer solution, then add it to the formulation and stir thoroughly.


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