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214047-00-4
  • Product Name:Palmitoyl Pentapeptide-4 (Matrixyl)
  • Efficacy:Mimics collagen fragments to stimulate repair
  • Application:Cosmetic ingredients
  • Molecular:C39H75N7O10
Product Details

Palmitoyl pentapeptide-4 (Matrixyl/Pentapeptide) Product Promotion Copy


I. Basic Product Information

Chinese name: Palmitoyl pentapeptide-4 (commonly referred to as pentapeptide)

English name: Palmitoyl Pentapeptide-4/Matrixyl

CAS Number: 214047-00-4

Molecular formula: C39H75N7O10

Molecular weight: 802.05 g/mol

Amino acid sequence: pal-Lys-Thr-Thr-Lys-Ser-OH

Physical properties: White powder or transparent liquid (purity ≥95%)

Storage conditions: Lyophilized and stored away from light at-20°C

Package:100g per bag

MOQ 200g


II. Core Efficacy and Mechanism of Action

As the most established and widely used signaling-based anti-wrinkle peptide, palmitoyl pentapeptide-4 is hailed as a "alternative to botulinum toxin" and a "cell activator" for collagen production.Its core advantages lie in exceptional transdermal absorption and deep tissue repair capabilities:

Powerful collagen-stimulating agent: This component mimics the naturally degraded collagen fragments that occur during aging, delivering "repair signals" to dermal fibroblasts.Clinical studies have demonstrated that it can increase collagen synthesis by up to 350%, while stimulating the proliferation of elastin and hyaluronic acid, thereby reversing skin aging from the inside out.

Significant wrinkle reduction and firming: Specifically targets the depth and length of dynamic and static wrinkles (such as nasolabial folds, forehead lines, and periorbital fine lines), restoring skin fullness and structural integrity to achieve a more lifted and youthful appearance.

A gentle and highly effective anti-aging experience: Unlike irritating ingredients such as retinol, palmitoyl pentapeptide-4 exhibits exceptional mildness, delivering outstanding wrinkle-reduction efficacy without any side effects, making it suitable for long-term use on all skin types including sensitive skin.


III. Recommended Addition Ratios and Application Scenarios

This ingredient exhibits excellent formulation compatibility and can be formulated into various dosage forms including serums, creams, eye creams, lotions, and masks.

Daily anti-aging serum/cream: Recommended concentration is 0.001%–0.01% (based on pure powder).As a key anti-aging ingredient in daily skincare routines, its morning and evening application gradually enhances skin texture.

Eye care (eye cream/eye serum): The recommended application concentration is 0.005%–0.01%.Specifically designed for the delicate eye area, it effectively reduces fine wrinkles and improves skin laxity.

High-end anti-wrinkle mask/ampoule: Recommended concentration range is 0.01%–0.05%.As a intensive repair product, it delivers deep penetration and long-lasting wrinkle-reducing effects.


IV. Formulation Recommendations and Safety Compliance

Optimal Gold Combination: It can be perfectly formulated with hyaluronic acid (to enhance hydration and volume) and vitamin C (for antioxidant effects and promotion of collagen synthesis). When combined with retinol, it is recommended to use them at different times or in low concentrations to maximize wrinkle-reducing efficacy.

Usage precautions: This component exhibits optimal performance in systems with a pH range of 4.0 to 7.0. Concurrent use with highly concentrated acidic components (e.g., acetic acid or salicylic acid) should be avoided to prevent reduction of efficacy.

Safety and Compliance: As a cosmetic-grade peptide ingredient, it exhibits superior wrinkle-reducing efficacy and biological activity compared to conventional vitamin A and C, while being free from irritant side effects, making it an ideal core component for developing safe and highly effective anti-aging skincare products.


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