Tetrapeptide-4/Pep UP Product Promotion 

1、 Product basic file

Chinese name: Tetrapeptide-4

English name: Tetrapeptide-4 (commercial alias: Pep UP)

CAS number: 960608-16-6

Molecular formula: C ₁₄ H ₂₂ N ₄ O ₇

Molecular weight: 358.35 g/mol

Amino acid sequence: Gly Glu Pro Gly (glycine glutamic acid proline glycine), abbreviated as GEPG

Appearance specifications: White to off white solid powder (purity ≥ 95%)

Solubility: Good water solubility (In Vitro: DMSO solubility can reach 33.33 mg/mL, ultrasound assisted dissolution is required)

Storage conditions: The powder should be sealed and kept away from light, and can be frozen at -20 ℃ for 1-2 years; After preparing the solution, it needs to be divided and stored at -80 ℃ for 6 months to avoid repeated freeze-thaw cycles leading to deactivation

2、 Core efficacy and mechanism of action

Tetrapeptide-4 is a novel biomimetic tetrapeptide, whose core mechanism of action is to increase skin density by self stimulating the generation of connective tissue components, effectively combating gravity and maintaining a youthful appearance. Its core functions are mainly reflected in the following dimensions:

Lifting Tightening and Anti Relaxation: Tetrapeptide-4 can challenge the influence of gravity on the skin, endowing it with significant "lifting" and "boosting up" effects, making facial contours clearer and effectively improving skin sagging and laxity.

Strong promotion of extracellular matrix (ECM): As a signaling active substance, tetrapeptide-4 can significantly increase the production of collagen, elastin, and fibronectin in the skin. These matrix proteins are crucial for maintaining the integrity and elasticity of skin structure, and their increased synthesis can fundamentally enhance skin density.

Deep wrinkle resistance and smooth skin texture: By promoting the generation of dermal fibers, tetrapeptide-4 can significantly reduce the depth of wrinkles, refine wrinkle texture, make the skin surface smoother, and improve overall skin quality.

Multiple protection and comprehensive anti-aging: In addition to basic anti-aging and firming, Tetrapeptide-4 also has blue light protection and photoaging protection capabilities, which can even out skin tone, promote skin regeneration and rejuvenation, and maintain healthy and radiant skin. In addition, in the field of hair care, it has been proven to have the potential to delay hair whitening and prevent hair loss.

3、 Recommended addition ratio and application scenarios

The tetrapeptide-4 formula has excellent compatibility and cold processability, and can be widely used in various personal care formulas.

Anti aging and firming essence/face cream: as the core anti-aging ingredient, it is recommended to add it according to the concentration of active solution provided by the raw material manufacturer. Daily use can effectively promote collagen synthesis, resist gravity, and enhance skin firmness and contour.

Intensive repair facial mask/ampoule: suitable for high concentration intensive facial care products, focusing on improving deep wrinkles, skin relaxation and signs of light aging.

Hair care and scalp care products: can be used in hair film, hair care essence and anti hair loss shampoo, and use its characteristics of delaying hair whitening and preventing hair loss to create healthy and strong hair.

Sunscreen and post sun repair products: With its photoaging protection and soothing properties, it can be compounded in sunscreen or post sun repair gel to reduce the damage of ultraviolet and blue light to the skin.

4、 Formula recommendations and safety compliance

Gold synergistic combination: can be combined with various anti-aging ingredients to build a comprehensive protective system. For example, combining antioxidants (such as vitamin C derivatives) to enhance the anti photoaging effect; Paired with moisturizers (such as hyaluronic acid) to enhance skin fullness; In hair care products, it can be combined with nourishing oils to improve the appearance of hair.

Compatibility and process advantages: Tetrapeptide-4 has good water solubility and supports cold blending process, greatly simplifying the production process and reducing the risk of deactivation of thermosensitive components. Its biomimetic structure is gentle and suitable for all skin types.

Safety compliance: Tetrapeptide-4 has been included in China's "Catalogue of Used Cosmetic Ingredients" (IECIC) and meets domestic cosmetic regulatory requirements. At the same time, this ingredient complies with the Sephora "Clean at Sephora" label statement, has high safety, and is widely used in the high-end skincare and hair care markets.

5、 Application areas and brand usage display

Tetrapeptide-4 is widely used in the global personal care market, covering multiple fields such as facial skincare, hair care, sun protection, and makeup contouring.

High end anti-aging skin care products: they are used by many international and domestic famous brands in high-end face cream and essence that focus on the concepts of "lifting and tightening", "combating gravity" and "light lines".

Professional hair care brand: It is used in essence liquid and washing set that mainly focus on "preventing hair loss and fixation", "delaying white hair" and "scalp anti-aging".

Domestic record product case: For example, the "PTX Peptide Energy Muscle Activating Multi effect Brightening Cream" (record number: Guozhuang Net Bei Jin Zi (Zhe) 2021000803) produced by Kaijian Biotechnology Co., Ltd. in South Korea clearly adds tetrapeptide-4 in its ingredient list and synergizes with plant ingredients such as buckwheat seed extract and wild soybean oil, focusing on multi effect brightening and anti-aging.