Palmitoyl Hexapeptide-14

1、 Product basic file

Chinese name: Palmitoyl Hexapeptide-14 (formerly known as Palmitoyl Hexapeptide-6)

English name: Palmitoyl Hexapeptide-14/Palmitoyl Hexapeptide-6

CAS number: 891498-01-4

Molecular formula: C ₅₂ H ₉₂ N ₈ O ₇

Molecular weight: 941.34 g/mol

Amino acid sequence: {Pal-Phe}-Ala-Leu-Leu-Lys-Leu-NH ₂

Appearance specifications: white powder, purity usually ≥ 98%

Solubility: soluble in water

Storage conditions: The powder state should be sealed and protected from light. It can be frozen at -20 ℃ for up to 3 years and stored at 4 ℃ for 2 years; After preparing the solution, it needs to be divided and stored at -80 ℃ for 6 months and -20 ℃ for 1 month to avoid repeated freezing and thawing

2、 Core efficacy and mechanism of action

Palmitoyl hexapeptide-14 is a short chain bioactive peptide modified with palmitoyl, which significantly enhances its delivery effect in the skin. Its core efficacy and mechanism of action are mainly reflected in the following dimensions:

Retinol like anti-aging and collagen regeneration (core efficacy): Palmitoyl hexapeptide-14 is known as a novel "retinol" peptide, which has a collagen promoting function similar to retinol (retinol), but is warmer and less irritating. Human efficacy tests have shown that its ability to reduce fine lines and wrinkles is comparable to retinol, and it is very suitable for use on sensitive muscles.

Inhibition of matrix metalloproteinases (MMPs): This component can block the activity of MMP-9 collagenase, thereby inhibiting the degradation of collagen and effectively protecting the skin matrix from damage.

Promoting fibroblast proliferation and collagen synthesis: It can stimulate the production of collagen and promote fibroblast proliferation, fundamentally improving signs of skin aging through the repair and regeneration of tissue construction processes.

Anti inflammatory and skin improvement: It has a clear anti-inflammatory effect and helps to improve skin dullness and dryness caused by aging, restoring healthy radiance to the skin.

3、 Recommended addition ratio and application scenarios

Palmitoyl hexapeptide-14 formula has good compatibility and can be widely used in various personal care formulas.

Anti wrinkle and firming essence/face cream: as the core active ingredient, it provides precise and light line care for facial fine lines and wrinkles to improve skin tightness and elasticity.

Sensitive muscle anti-aging product: use its "retinol like" effect but non irritating properties to design a mild and efficient anti-aging lotion and essence for sensitive muscle and skin with poor tolerance.

Eye care products: used in eye cream, eye essence, etc., to promote collagen synthesis and reduce fine lines, and improve signs of aging around the eyes.

Soothing and repairing products: Combined with their anti-inflammatory properties, they can be applied to soothe and reshape damaged skin.

4、 Formula recommendations and safety compliance

Gold synergy combination:

Compound with Korean ginseng extract: Studies have shown that the combination of palmitoyl hexapeptide-14 and Korean ginseng extract can significantly inhibit MMP-9 function and synergistically exert stronger anti wrinkle effects.

Compound with other peptides: It can be combined with ingredients such as acetyl hexapeptide-8 (botulinum toxin like peptide) to construct a full chain anti-aging system that promotes collagen production and inhibits muscle contraction.

Compatibility and process suggestions: This ingredient belongs to the signal active peptide category, and it is recommended to add it at a low temperature during the post formulation stage to maximize its biological activity. After preparing the solution, it should be packaged and stored separately to avoid repeated freezing and thawing.

Safety compliance: Independent studies have shown that palmitoyl hexapeptide-14 is non cytotoxic, non mutagenic, non irritating, and non allergenic. Extremely safe, suitable for sensitive skin.

5、 Application Fields and Market Supply

Palmitoyl hexapeptide-14, as a novel collagen regenerating peptide, is widely used in the high-end anti-aging skincare market.