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  • Product Name:Hexapeptide-10 (Serilesine)
  • Efficacy:Anti-aging
  • Application:Cosmetic ingredients
  • Molecular:C28H53N7O8
Product Details

Other Name: serilesine; H-SER-ILE-LYS-VAL-ALA-VAL-OH

Molecular Weight: 615.76

Appearance: White powder

Purity: >99%

Package: 100G/bottle; 500G/bottle; 1kg/bottle


*Hexapeptide-10 comes from the adhesion sequence of laminin,which restores the structure of the skin.


*Serilesine is a firming active substance that promotes the dual cell activity of keratinocytes and fibroblasts.

Serilesine hexapeptide 10 increases the synthesis of laminin 5,α6-integrin and semi-liposomes,thereby enhancing 

the dermal-epidermal junction.Hexapeptide-10 can reshape,replenish,firm and elastic skin,and restore its fullness.

The skin is restructured and replenished (the skin density increases by 19% after 2 months), becomes firmer and 

more elastic,and restores fullness.


★What is Hexapeptide-10?

Hexapeptide-10 is a synthetic bioactive peptide composed of six amino acids. It mimics cell adhesion molecules, 

helping to improve skin structure, firmness, and overall appearance.


★Is Hexapeptide-10 safe?

Yes, Hexapeptide-10 is considered safe for topical use in cosmetics when used within recommended concentrations. 

It is widely used in anti-aging and firming formulations.


★What is the recommended usage rate of Hexapeptide-10 in cosmetics?

Typical addition level: 0.001%–0.005% (10–50 ppm). It works in serums, emulsions, creams, gels, masks, and eye care. 

Start at 0.002% for stable efficacy; adjust based on formula positioning and cost.


★What is the solubility of Hexapeptide-10?

Hexapeptide-10 is generally water-soluble and can be easily incorporated into aqueous systems such as serums and emulsions.


★What pH range and formulation systems is Hexapeptide-10 compatible with?

Stable in pH 4.5–7.0 (best at 5.0–6.5). Compatible with water-based, oil-in-water (O/W), water-in-oil (W/O), gel, and clear 

serum systems. Avoid strong oxidants, high temperatures (>60°C), and extreme pH to preserve peptide activity.


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