Other Name: syn coll peptide; SYN-COL

Molecular Weight: 839.95

Appearance: White powder

Purity: >98%

Package: 100G/bottle; 500G/bottle; 1KG/bottle

*Palmitoyl Tripeptide-5 belongs to the signaling peptide class and is the most widely used cosmetic small molecule peptide. 

Its cosmetic efficacy is comparable to that of injecting collagen.

Research has shown that such peptides promote the synthesis of collagen (types I, II, and IV) and the generation of extracellular 

matrix proteins by increasing stromal cell activity, strengthening connective tissue, promoting cell activity, and making the skin 

appear younger and more elastic. Many famous foreign cosmetics brands (such as Est é e Lauder, Chanel, Avon, etc.) use palmitoyl tripeptide-5 

as a nutritional anti wrinkle ingredient because it has the ability to promote the synthesis of collagen and elastin in the dermis, making it 

an ideal raw material for accelerating collagen production and repairing wrinkles. Adding it to cosmetics can help the skin replenish collagen, 

enhance facial elasticity, and significantly reduce facial wrinkles. At the same time, it also has the characteristics of enhancing cell activity, 

increasing skin moisture content, enhancing skin gloss, and improving skin tone. In addition, it also has the effect of moisturizing the lips.

★What is Palmitoyl Tripeptide-5 and what makes it unique?

Palmitoyl Tripeptide-5 (CAS: 623172-56-5, Pal-KVK) is a lipopeptide that mimics TGF-β activity. Unlike general collagen stimulators, 

it activates the TGF-β/Smad pathway to specifically regenerate Type I and III collagen, addressing the root cause of skin elasticity loss.

★What is the collagen regeneration mechanism?

It binds to TGF-β receptors on dermal fibroblasts, activating Smad signaling to upregulate Type I (80% of dermal collagen) and Type III 

(youthful elasticity) collagen genes. The palmitoyl modification achieves 78% dermal penetration, 3x higher than non-modified peptides.

★What is the recommended dosage?

Standard usage rate is 1% to 5% in finished formulations. For anti-wrinkle serums and firming creams, 2-3% is typical. For daily 

moisturizers and eye treatments, 1-2% provides effective results. Purity is ≥99% as lyophilized powder.